open-discussion > clinically relevant populations?
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Aug 16, 2010  08:08 PM | Arno Klein
clinically relevant populations?
are any of the datasets acquired from a clinically relevant as well as control population, or are all of the data from control (normal healthy) individuals?

cheers,
@rno
Aug 16, 2010  09:08 PM | Clare Kelly
RE: clinically relevant populations?
Hi Arno,

Yes - as part of the NYU data release there are scans from 25 adults with ADHD. If you scroll about half-way down the data page and you will find NewYork_a_ADHD.tar (n = 25 [19M/4F]; ages: 20-50; TR = 2; # slices = 39; # timepoints = 192). These data included in the publications by Castellanos et al. (2008) and Uddin et al. (2008), which I have attached here.

Best,
Clare
Aug 16, 2010  09:08 PM | Clare Kelly
RE: clinically relevant populations?
Uddin paper attached
Aug 16, 2010  09:08 PM | Arno Klein
RE: clinically relevant populations?

thank you very much!

cheers,
@rno
Aug 18, 2010  07:08 PM | Arno Klein
RE: clinically relevant populations?

were the nyu images acquired using PACE? if so, did it also have GRAPPA acceleration?

i have run the adhd and part1 datasets through nipype (nipy.org/nipype) and rapidart artifact detection (within nipype) and found there to be very little motion. there were 14 subjects altogether that have motion exceeding 1mm at the center of at least one of the faces of the brains' bounding boxes for at least one of the volumes.

cheers,
@rno
Aug 18, 2010  07:08 PM | Maarten Mennes
RE: clinically relevant populations?
Hi Arno,

we are not sure what you mean by PACE? In any case there was no GRAPPA acceleration or parallelization. It was a standard EPI sequence on an Allegra 3T head only scanner.

Good that you are looking at the quality of the data! We did not release subjects that had significant motion, but yes there are some subjects that have motions exceeding 1mm.

Best,
Maarten
Aug 18, 2010  07:08 PM | Arno Klein
RE: clinically relevant populations?

thank you. pace = "prospective acquisition correction" and is a siemens algorithm for k-space modification to account for inter-tr movement.

cheers,
@rno
Aug 18, 2010  08:08 PM | Maarten Mennes
RE: clinically relevant populations?
Hi Arno,

nope, we don't have PACE then.

Also another note on the motion in the ADHD subjects. Just want to make sure you know they are all adults [which helps in having less motion ;)]

best,
Maarten
Aug 18, 2010  09:08 PM | Arno Klein
RE: clinically relevant populations?

interestingly, i found twice as many part1 controls with motion outliers as adhd subjects with motion outliers!

cheers,
@rno
Aug 19, 2010  01:08 PM | Maarten Mennes
RE: clinically relevant populations?
Hi Arno,

is that percent-wise or in absolute numbers? You should look at the percentage, as there are more controls compared to ADHD.

cheers,
Maarten
Aug 19, 2010  02:08 PM | Arno Klein
RE: clinically relevant populations?

absolutely!

@
Nov 8, 2010  03:11 PM | Yong Fan
RE: clinically relevant populations?
Is it possible to have the slice timing information for this dataset?
Nov 8, 2010  05:11 PM | Maarten Mennes
RE: clinically relevant populations?
Hi Yong Fan,

the slice time information is under Docs/Release_Table. For the NYU datasets the slice acquisition order is: interleaved ascending.

Hope this helps,
Maarten