help > dmn seed definition rationale?
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Apr 12, 2016  11:04 AM | Clas Linnman
dmn seed definition rationale?
Hi, I was wondering how you came up with the dmn seed definitions in conn, specifically, the PCC seed seems to be centered at -7, -52, 39 if I am not mistaken. I see lots of other papers define the default mode PCC as centered at 0, -53,26.
Is there a reference/rationale for putting it at -7, -52, 39 in conn?

Best
Clas Linnman
Apr 15, 2016  01:04 PM | Alfonso Nieto-Castanon - Boston University
RE: dmn seed definition rationale?
Hi Clas,

The dmn seed definitions in the "dmn" file were defined from the coordinates reported in Fox et al. PNAS 2005 paper. These may be a bit outdated now, in the next CONN release we are hoping to add a more extensive set of seeds for the default-mode network as well as other networks of interest derived from Independent Component Analyses of the HCP dataset, which may prove more generalizable. 

Hope this helps
Alfonso
Originally posted by Clas Linnman:
Hi, I was wondering how you came up with the dmn seed definitions in conn, specifically, the PCC seed seems to be centered at -7, -52, 39 if I am not mistaken. I see lots of other papers define the default mode PCC as centered at 0, -53,26.
Is there a reference/rationale for putting it at -7, -52, 39 in conn?

Best
Clas Linnman
Apr 26, 2016  01:04 PM | Clas Linnman
RE: dmn seed definition rationale?
thanks!
Jan 10, 2019  12:01 PM | Edward Watson
RE: dmn seed definition rationale?
Hi Alfonso,

I was wondering if there is an update on this, does Conn still use the coordinates from the Fox et al. PNAS 2005 paper?

Thank you for all your hard work putting this toolbox together.

Best wishes,

Ed