Dear moderator,

I have just read your paper (https://www.frontiersin.org/articles/10....) which was very informative, and I am very excited to try to apply your toolbox to my data. I have just one question about the stimulus duration before i do so. I've noted that you've recommended that the stimulus duration should be >TR, otherwise the outcome measures will fit to noise. 

For each trial of my experimental task, the participant needs to respond twice (at Stimulus 1 and Stimulus 2). The timing of the stimuli within each trial is as follows:
- Stimulus 1 (<2s)
- Feedback 1 (1.5s)
- Stimulus 2 (<2s)
- Feedback 2 (1.5s)
- Feedback 3 (1.5s)
- ITI (jittered, 1-7s)
- TR (2.41s)

In this case, would you recommend using your toolbox for investigating task-related connectivity, or would it be too noisy, given that there are multiple events within a trial and each of which are less than one TR?

Your help will be much appreciated. Thank you.

With kind regards,
Ying

Dear Ying,

I think under these circumstanes you will not get reliable or meaningful results as the TR ist large compared to the stimulus durations.

Best,

Martin