Hi Kumar,

I agree with Emilie, if you are not doing tractography you do not necessarily need to update the parameter's files for each subject.

If you have matlab, and feel comfortable with a little bit of coding, I've attached a script that can help you batch process this and update the parameters for each subject automatically. I've also included a few lines of code where I've used this in the past (you will have to modify this and define your own variables to make this work... it's just included as an example).

Best,

Russell



file_paths.dke = '~/Documents/DKE_2.6'; %Directory with dke executable file

new_params = {'studydir',sprintf('''%s''',file_paths.output),'subject_list','{''''}',...
'fn_gradients',sprintf('''%s''',file_paths.dki_grad),...
'fwhm_img',sprintf('1.25*[%d %d %d]',vox(1),vox(2),vox(3)),'preprocess_options.format','''nifti''',...
'preprocess_options.fn_nii','''dki_4D''','ndir',sprintf('%d',ndir),...
'T',sprintf('%d',dke_mask_threshold),'idx_gradients',idx_gt_str,'bval',bt_str,'median_filter_method','0'};

updateParametersFile(file_paths.dke_params_template,file_paths.dke_params_new,new_params);

%Run DKE
cd(file_paths.dke)
if isunix; eval(sprintf('!./dke ''%s''',file_paths.dke_params_new))
elseif ispc; eval(sprintf('!dke %s',file_paths.dke_params_new))
end