help > "no significant voxels"
Nov 3, 2017  06:11 PM | Patrick McConnell - MUSC
"no significant voxels"
I am also having the same "no significant voxels" problem.... 

Originally posted by kito24:
Hi Alfonso and Chaleece,

Were you able to figure out a solution to this problem? I'm running into a similar bug; I tried to use preprocessed data from Conn following previous posts in the topic (converting the preprocessed .mat file to niftis, and then splitting those by sessions) but I'm also running into a similar error:

Error using spm_est_non_sphericity (line 196)
Please check your data: There are no significant voxels.

Error in spm_spm (line 421)
[xVi, am] = spm_est_non_sphericity(SPM);
Error in spm_getSPM (line 234)
SPM = spm_spm(SPM);
Error in spm_results_ui (line 261)
[SPM,xSPM] = spm_getSPM;
Error while evaluating uicontrol Callback


I also tried running this line but still have the same error.

spm.stats.fmri_spec.mthresh=-inf 

Please let me know if you have a solution to this! 

Thanks,
Kaori



Originally posted by Alfonso Nieto-Castanon:
Hi Chaleece,

Sorry about that. If you could please send me your conn*.mat project file and the script that you are using for SPM first-level analyses I will be happy to take a closer look to see if I can figure out the source of this issue.

Best
Alfonso
 
Originally posted by Chaleece Sandberg:
Hi Alfonso!
I have bad news. I am getting the same error with the threshold change you suggested. Do you know what else the problem may be? Could it be something in the way I'm setting up the Denoising step? I believe I verified all that during the conference call, but I could be missing something. 
Thanks!
Chaleece
Originally posted by Alfonso Nieto-Castanon:
Hi Chaleece,

This indicates that SPM finds no significant "any condition/task effects" in your data. There are several potential reasons, my best guess is that this is related to the explicit masking of the analyses combined with the band-pass filtering of your original data (by default SPM will look for "in-brain" voxels by comparing their average BOLD signal to the average global BOLD signal; since your data is band-pass filtered the average BOLD signal is always 0). I would suggest to change in your script the line  "spm.stats.fmri_spec.mthresh=.8" to ""spm.stats.fmri_spec.mthresh=-inf" in order to skip this implicit masking altogether. Please let me know if that does not seem to be the issue here. 

Best
Alfonso

Originally posted by Chaleece Sandberg:
Hello again,
I hate to be a bother, but I have now run into another problem when I try to actually run the GLM in SPM:

Running 'Model estimation'

SPM12: spm_spm (v6015) 11:58:27 - 06/08/2015
========================================================================
SPM12: spm_est_non_sphericity (v6015) 11:58:30 - 06/08/2015
========================================================================
Chunk 97/97 : ...processing
Failed 'Model estimation'
Error using spm_est_non_sphericity (line 196)
Please check your data: There are no significant voxels.
In file "C:\Users\Public\Documents\spm12\spm_est_non_sphericity.m" (v6015), function "spm_est_non_sphericity" at line 196.
In file "C:\Users\Public\Documents\spm12\spm_spm.m" (v6015), function "spm_spm" at line 418.
In file "C:\Users\Public\Documents\spm12\config\spm_run_fmri_est.m" (v5809), function "spm_run_fmri_est" at line 33.
The following modules did not run:
Failed: Model estimation

Does this mean that the Denoising step somehow reduced any significance? I didn't include the conditions as confounds for denoising. I am attaching my my batch for spm, if that helps. Would you like the conn.mat file?

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TitleAuthorDate
Roger Beaty Jun 12, 2014
Leah Fleming Nov 23, 2016
kito24 Feb 7, 2017
Laila Franke Dec 19, 2018
Pravesh Parekh Dec 19, 2018
Leah Fleming Feb 8, 2017
Alfonso Nieto-Castanon Jun 13, 2014
Chaleece Sandberg Jul 31, 2015
Alfonso Nieto-Castanon Aug 3, 2015
Chaleece Sandberg Aug 5, 2015
Nole Hiebert Aug 23, 2018
Alfonso Nieto-Castanon Aug 6, 2015
Chaleece Sandberg Aug 6, 2015
Chaleece Sandberg Aug 6, 2015
Alfonso Nieto-Castanon Aug 6, 2015
laurentcohen Sep 14, 2018
Chaleece Sandberg Oct 2, 2015
Alfonso Nieto-Castanon Oct 8, 2015
kito24 Feb 9, 2017
Ines Del Cerro Nov 9, 2017
"no significant voxels"
Patrick McConnell Nov 3, 2017
Roger Beaty Jan 26, 2015
Alfonso Nieto-Castanon Jan 27, 2015
Roger Beaty Jan 27, 2015
Alfonso Nieto-Castanon Jan 29, 2015
laurel morris Mar 11, 2016
Alfonso Nieto-Castanon Mar 14, 2016
Isabel Berwian Nov 28, 2016
Anila D'Mello Nov 10, 2015
Roger Beaty Jun 14, 2014