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help > RE: Excitation vs. Inhibition
Feb 20, 2020 02:02 AM | Donald McLaren
RE: Excitation vs. Inhibition
PPI does not show causation.
While the results of A-->B is not the same as B-->A, the method isn't sensitive to the direction or cause of the effect.
All that we can say is the the slope of the of the relationship between A and B is greater in one task compared to another. This could be due to A being less active in one condition and B being relatively the same across both conditions.
In your interpretation of the PPI results, I would not try to explain the underlying biology as there are numerous reasons the connectivity could change.
While the results of A-->B is not the same as B-->A, the method isn't sensitive to the direction or cause of the effect.
All that we can say is the the slope of the of the relationship between A and B is greater in one task compared to another. This could be due to A being less active in one condition and B being relatively the same across both conditions.
In your interpretation of the PPI results, I would not try to explain the underlying biology as there are numerous reasons the connectivity could change.
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Title | Author | Date |
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Phil Kuhnke | Feb 10, 2020 | |
Donald McLaren | Feb 20, 2020 | |