Hello,

I am delighted to have discovered the semi-partial correlation feature but have a question:
When using bivariate correlation S2V with a given seed I obtain, for example, I do not observe FC between my seed and the amygdala (using TFCE on n=135 data). When I use semi-partial with the same seed controlling for another nearby region (my ideal analysis) I DO obtain FC between my seed of interest and the amygdala (same thresholding TCFE approach).

How is it possible to not obtain a connection between two regions using bivariate but to observe a significant connection when controlling for another area?

Thank you!
Sarah