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help > RE: ANOVA 2*2 with between and within factors vs. with only within factors , design & exchange blocks
Jan 10, 2026 07:01 PM | Philippe Peigneux
RE: ANOVA 2*2 with between and within factors vs. with only within factors , design & exchange blocks
Dear Andrew
there is some ambiguity in your description but I will do my
best to answer.
Apologies if my description was ambiguous, and thanks for the effort 😊
What you have described in (1) is all correct. But I assume that the subjects in group A are distinct individuals compared to the subjects in group B. If they are instead the same subjects, you may want to include a single column within-subject mean for each subject rather than modeling the within-subject mean separately for each group.
Here it is indeed 2 distinct groups with different individuals, thus a 2*2 anova with one between- (group) and one within- (day) subject factors
For option (2), I am a little confused about the set up. I
wasn't sure if you mean that subjects can potentialluy crossover
from one group to another at the second measuremnt. If this is not
the case, and you rather have more than two repeated
measurments, you may want to consider inference on the slopes
(rates of changes) acorss the time points.
No, actually in my real study I have 3 factors in total but 2*2*2
anova are definitely impossible to implement and even more to
interpret 😊 In option (2) each subject is recorded 4 times (A and B
at day 1, A and B at day 2) and there is no group factor, thus it
is full within-subject repeated measurement anova. Since it is the
same subjects, based on your answer to option (1) I would include a
single column within-subject mean for each subject.
By inference on the slopes (rates of changes) across the time
points, do you mean e.g. subtracting (or computing % change)
matrices A and B , and then use the resulting matrices to compare
time points day 1 and day 2 ?
Thanks a lot and best regards,
Philippe
Threaded View
| Title | Author | Date |
|---|---|---|
| Philippe Peigneux | Jan 9, 2026 | |
| Andrew Zalesky | Jan 9, 2026 | |
| Philippe Peigneux | Jan 10, 2026 | |
| Andrew Zalesky | Jan 10, 2026 | |
| Philippe Peigneux | Jan 9, 2026 | |