The Turone Sheep Brain Templates and Atlas (TSBTA) resources offer to the preclinical neuroimaging community a complete set of in vivo templates, tissues priors of the sheep brain for both sex as well as a mixed template and its associated priors. Additionnaly, we provide a complete anatomical atlas covering the entire brain. This new set of resources allows both linear and non-linear coregistration of multimodal acquisitions performed on the same animal (functional, anatomical and diffusion), leading to an accurate identification of the brain territories involved in a physiological or pathophysiological process. The TSBTA resources pave the way for standardization of preclinical MRI and neurosciences research in large animals.