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Oct 15, 2012 Resting State fMRI-guided Fiber Clustering: Methods and Applications
Abstract  Clustering streamline fibers derived from diffusion tensor imaging (DTI) data into functionally meaningful bundles with group-wise correspondences across individuals...
Oct 10, 2012 Asymmetry of the Dorsal Anterior Cingulate Cortex: Evidences from Multiple Modalities of MRI
Abstract  The dorsal anterior cingulate cortex (dACC) has been consistently implicated in cognitive control processes. Many studies have found higher fractional anisotropy...
Oct 7, 2012 Towards Semi-Automatic Reconstruction of Neural Circuits
Towards Semi-Automatic Reconstruction of Neural Circuits Content Type Journal ArticleCategory CommentaryPages 1-3DOI 10.1007/s12021-012-9166-xAuthors Albert Cardona, Janelia Farm...
Oct 3, 2012 Automated Segmentation of Mouse Brain Images Using Multi-Atlas Multi-ROI Deformation and Label Fusion
Abstract  We propose an automated multi-atlas and multi-ROI based segmentation method for both skull-stripping of mouse brain and the ROI-labeling of mouse brain structures...
Sep 30, 2012 Meta-Analysis of Functional Roles of DICCCOLs
Abstract  DICCCOL (Dense Individualized and Common Connectivity-based Cortical Landmarks) is a recently published system composed of 358 cortical landmarks that possess consistent...
Sep 30, 2012 iBEAT: A Toolbox for Infant Brain Magnetic Resonance Image Processing
Abstract  It’s a great challenge to analyze infant brain MR images due to the small brain size and low contrast of the developing brain tissues. We have developed an Infant...
Sep 19, 2012 Ten Years of Neuroinformatics
Ten Years of Neuroinformatics Content Type Journal ArticleCategory EditorialPages 1-2DOI 10.1007/s12021-012-9162-1Authors Erik De Schutter, Computational Neuroscience Unit, Okinawa...
Sep 14, 2012 Obscuring Surface Anatomy in Volumetric Imaging Data
Abstract  The identifying or sensitive anatomical features in MR and CT images used in research raise patient privacy concerns when such data are shared. In order to protect...
Sep 9, 2012 A Systems-Level Approach to Human Epileptic Seizures
Abstract  Epileptic seizures are due to the pathological collective activity of large cellular assemblies. A better understanding of this collective activity is integral...
Sep 6, 2012 Detecting Brain State Changes via Fiber-Centered Functional Connectivity Analysis
Abstract  Diffusion tensor imaging (DTI) and functional magnetic resonance imaging (fMRI) have been widely used to study structural and functional brain connectivity in recent...
Sep 2, 2012 System for Integrated Neuroimaging Analysis and Processing of Structure
Abstract  Mapping brain structure in relation to neurological development, function, plasticity, and disease is widely considered to be one of the most essential challenges...
Aug 20, 2012 FocusDET, A New Toolbox for SISCOM Analysis. Evaluation of the Registration Accuracy Using Monte Carlo Simulation
Abstract  Subtraction of Ictal SPECT Co-registered to MRI (SISCOM) is an imaging technique used to localize the epileptogenic focus in patients with intractable partial epilepsy....
Aug 12, 2012 A Statistical Framework for Inter-Group Image Registration
Abstract  Groupwise image registration plays an important role in medical image analysis. The principle of groupwise image registration is to align a given set of images...
Jun 6, 2012 The Benefits of Preparing Data for Sharing Even When You Don’t
The Benefits of Preparing Data for Sharing Even When You Don’t Content Type Journal ArticleCategory EditorialPages 1-2DOI 10.1007/s12021-012-9154-1Authors David N. Kennedy, Division...
Jun 3, 2012 Semi-Automated Neuron Boundary Detection and Nonbranching Process Segmentation in Electron Microscopy Images
Abstract  Neuroscientists are developing new imaging techniques and generating large volumes of data in an effort to understand the complex structure of the nervous system....
Jun 3, 2012 Three-Dimensional Analysis of Spiny Dendrites Using Straightening and Unrolling Transforms
Abstract  Current understanding of the synaptic organization of the brain depends to a large extent on knowledge about the synaptic inputs to the neurons. Indeed, the dendritic...
Jun 3, 2012 Development of PowerMap: a Software Package for Statistical Power Calculation in Neuroimaging Studies
Abstract  Although there are a number of statistical software tools for voxel-based massively univariate analysis of neuroimaging data, such as fMRI (functional MRI), PET...
May 27, 2012 Sharing Heterogeneous Data: The National Database for Autism Research
Abstract  The National Database for Autism Research (NDAR) is a secure research data repository designed to promote scientific data sharing and collaboration among autism...
May 25, 2012 Morphological Homogeneity of Neurons: Searching for Outlier Neuronal Cells
Abstract  We report a morphology-based approach for the automatic identification of outlier neurons, as well as its application to the NeuroMorpho.org database, with more...
Apr 16, 2012 Principal Curves as Skeletons of Tubular Objects
Abstract  Developments in image acquisition technology make high volumes of neuron images available to neuroscientists for analysis. However, manual processing of these images...
Apr 16, 2012 What’s Black and White About the Grey Matter?
Abstract  In 1873 Camillo Golgi discovered his eponymous stain, which he called la reazione nera. By adding to it the concepts of the Neuron Doctrine and the Law of Dynamic...
Apr 16, 2012 Models and Simulation of 3D Neuronal Dendritic Trees Using Bayesian Networks
Abstract  Neuron morphology is crucial for neuronal connectivity and brain information processing. Computational models are important tools for studying dendritic morphology...
Apr 16, 2012 Dataset of Magnetic Resonance Images of Nonepileptic Subjects and Temporal Lobe Epilepsy Patients for Validation of Hippocampal Segmentation Techniques
Abstract  The hippocampus has become the focus of research in several neurodegenerative disorders. Automatic segmentation of this structure from magnetic resonance (MR) imaging...
Apr 16, 2012 A Broadly Applicable 3-D Neuron Tracing Method Based on Open-Curve Snake
Abstract  This paper presents a broadly applicable algorithm and a comprehensive open-source software implementation for automated tracing of neuronal structures in 3-D microscopy...
Apr 16, 2012 A Brief History of Neuronal Reconstruction
A Brief History of Neuronal Reconstruction Content Type Journal ArticleCategory CommentaryPages 119-128DOI 10.1007/s12021-011-9107-0Authors Stephen L. Senft, Krasnow Institute for...
Apr 16, 2012 An Open Source Multivariate Framework for n-Tissue Segmentation with Evaluation on Public Data
Abstract  We introduce Atropos, an ITK-based multivariate n-class open source segmentation algorithm distributed with ANTs (http://www.picsl.upenn.edu/ANTs). The Bayesian...
Apr 16, 2012 Automated Analysis of Fundamental Features of Brain Structures
Abstract  Automated image analysis of the brain should include measures of fundamental structural features such as size and shape. We used principal axes (P-A) measurements...
Apr 16, 2012 Tracking the Source of Quantitative Knowledge in Neuroscience: A Neuroinformatics Role for Computational Models
Tracking the Source of Quantitative Knowledge in Neuroscience: A Neuroinformatics Role for Computational Models Content Type Journal ArticleCategory EditorialPages 1-2DOI 10.1007/s12021-011-9100-7Authors John...
Apr 16, 2012 DIADEMchallenge.Org: A Compendium of Resources Fostering the Continuous Development of Automated Neuronal Reconstruction
DIADEMchallenge.Org: A Compendium of Resources Fostering the Continuous Development of Automated Neuronal Reconstruction Content Type Journal ArticleCategory News itemPages 303-304DOI...
Apr 16, 2012 Bright Field Neuronal Preparation Optimized for Automatic Computerized Reconstruction, a Case with Cerebellar Climbing Fibers
Bright Field Neuronal Preparation Optimized for Automatic Computerized Reconstruction, a Case with Cerebellar Climbing Fibers Content Type Journal ArticleCategory CommentaryPages 113-118DOI...
Apr 16, 2012 Neuronal Tracing for Connectomic Studies
Abstract  Reconstruction of the complete wiring diagram, or connectome, of a neural circuit provides an alternative approach to conventional circuit analysis. One major obstacle...
Apr 16, 2012 The DIADEM Metric: Comparing Multiple Reconstructions of the Same Neuron
Abstract  Digital reconstructions of neuronal morphology are used to study neuron function, development, and responses to various conditions. Although many measures exist...
Apr 16, 2012 Automated Reconstruction of Neural Tissue and the Role of Large-Scale Simulation
Automated Reconstruction of Neural Tissue and the Role of Large-Scale Simulation Content Type Journal ArticleCategory CommentaryPages 133-142DOI 10.1007/s12021-011-9114-1Authors James...
Apr 16, 2012 Axonal Reconstructions Going Live
Axonal Reconstructions Going Live Content Type Journal ArticleCategory CommentaryPages 129-131DOI 10.1007/s12021-011-9112-3Authors Alison J. Canty, MRC Clinical Sciences Centre,...
Apr 16, 2012 Inverse Current Source Density Method in Two Dimensions: Inferring Neural Activation from Multielectrode Recordings
Abstract  The recent development of large multielectrode recording arrays has made it affordable for an increasing number of laboratories to record from multiple brain regions...
Apr 16, 2012 The FARSIGHT Trace Editor: An Open Source Tool for 3-D Inspection and Efficient Pattern Analysis Aided Editing of Automated Neuronal Reconstructions
The FARSIGHT Trace Editor: An Open Source Tool for 3-D Inspection and Efficient Pattern Analysis Aided Editing of Automated Neuronal Reconstructions Content Type Journal ArticleCategory...
Apr 16, 2012 The DIADEM and Beyond
The DIADEM and Beyond Content Type Journal ArticleCategory EDITORIALPages 99-102DOI 10.1007/s12021-011-9102-5Authors Yuan Liu, National Institute of Neurological Disorders and Stroke...
Apr 16, 2012 Next Steps in Data Publishing
Next Steps in Data Publishing Content Type Journal ArticleCategory EditorialPages 317-320DOI 10.1007/s12021-011-9131-0Authors David N. Kennedy, Division of Neuroinformatics, Department...
Apr 16, 2012 Cerebral Aneurysms Database, a New Free Database for Intracranial Aneurysms
Cerebral Aneurysms Database, a New Free Database for Intracranial Aneurysms Content Type Journal ArticleCategory News ItemPages 427-430DOI 10.1007/s12021-011-9124-zAuthors Maurizio...
Apr 16, 2012 Automated Reconstruction of Dendritic and Axonal Trees by Global Optimization with Geometric Priors
Abstract  We present a novel probabilistic approach to fully automated delineation of tree structures in noisy 2D images and 3D image stacks. Unlike earlier methods that...
Apr 16, 2012 Automated Reconstruction of Neuronal Morphology Based on Local Geometrical and Global Structural Models
Abstract  Digital reconstruction of neurons from microscope images is an important and challenging problem in neuroscience. In this paper, we propose a model-based method...
Apr 16, 2012 Automated Tracing of Neurites from Light Microscopy Stacks of Images
Abstract  Automating the process of neural circuit reconstruction on a large-scale is one of the foremost challenges in the field of neuroscience. In this study we examine...
Apr 16, 2012 3-D Image Pre-processing Algorithms for Improved Automated Tracing of Neuronal Arbors
Abstract  The accuracy and reliability of automated neurite tracing systems is ultimately limited by image quality as reflected in the signal-to-noise ratio, contrast, and...
Apr 8, 2012 Volume Estimation of the Thalamus Using Freesurfer and Stereology: Consistency between Methods
Abstract  Freely available automated MR image analysis techniques are being increasingly used to investigate neuroanatomical abnormalities in patients with neurological disorders....
Apr 1, 2012 Information-Theoretic Approach for Automated White Matter Fiber Tracts Reconstruction
Abstract  Fiber tracking is the most popular technique for creating white matter connectivity maps from diffusion tensor imaging (DTI). This approach requires a seeding process...
Mar 25, 2012 The Connection-set Algebra—A Novel Formalism for the Representation of Connectivity Structure in Neuronal Network Models
Abstract  The connection-set algebra (CSA) is a novel and general formalism for the description of connectivity in neuronal network models, from small-scale to large-scale...
Mar 21, 2012 A WEKA Interface for fMRI Data
A WEKA Interface for fMRI Data Content Type Journal ArticleCategory News ItemPages 1-5DOI 10.1007/s12021-012-9144-3Authors M. Pyka, Department of Psychiatry, Philipps-Universität...
Mar 21, 2012 A Novel Group ICA Approach Based on Multi-scale Individual Component Clustering. Application to a Large Sample of fMRI Data
Abstract  Functional connectivity-based analysis of functional magnetic resonance imaging data (fMRI) is an emerging technique for human brain mapping. One powerful method...
Feb 24, 2012 Twenty Questions for Neuroscience Metadata
Twenty Questions for Neuroscience Metadata Content Type Journal ArticleCategory EditorialPages 1-3DOI 10.1007/s12021-012-9143-4Authors Giorgio A. Ascoli, Krasnow Institute for Advanced...
Feb 17, 2012 neuroVIISAS: Approaching Multiscale Simulation of the Rat Connectome
Abstract   neuroVIISAS is a generic platform which allows the integration of neuroontologies, mapping functions for brain atlas development, and connectivity data administration;...
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