[Neurobureau-hubs] [rs-fMRI QC protocol]
MCLAREN, Donald
mclaren.donald at gmail.com
Tue Aug 27 08:08:25 PDT 2013
I think this is a GREAT idea. Two things that are important to consider:
(1) pipeline independent QC metrics -- if someone is using another
pipeline, the QC metrics should still be applicable at least for the
pre-processing steps (e.g. motion, normalization, etc.)
(2) scanner/coil independent QC metrics -- I've seen some recent scanners
form high channel coils that don't have uniform intensities in the raw
images, this may or may not present a problem for standardizing QC metrics.
Either way, it should be a consideration.
We could potentially test the reliability at brainhack if you think we have
enough lead time to pilot some QC metrics. It should take too long for
everyone to QC 10-15 brains and you would get a good sample size. We could
reserve some time for training.
Best Regards, Donald McLaren
=================
D.G. McLaren, Ph.D.
Research Fellow, Department of Neurology, Massachusetts General Hospital and
Harvard Medical School
Postdoctoral Research Fellow, GRECC, Bedford VA
Website: http://www.martinos.org/~mclaren
Office: (773) 406-2464
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On Tue, Aug 27, 2013 at 1:08 AM, Cameron Craddock <
cameron.craddock at gmail.com> wrote:
> sounds great to me!
>
> -cc
>
>
>
> On Mon, Aug 26, 2013 at 8:51 PM, Pierre Bellec <pierre.bellec at criugm.qc.ca
> > wrote:
>
>> Dear hubs,
>>
>> I am posting on this list regarding one of the brainhack 2013 (ongoing)
>> project: quality control (QC) of processed rs-fMRI. I just heard a terrific
>> talk from Frissoni, and I think what we would want is something like that:
>> http://www.hippocampal-protocol.net/SOPs/index.php
>>
>> Basically
>> (1) set up a QC form,
>> (2) get a panel of experts to use it on a large database,
>> (3) get them to discuss conflicts,
>> (4) loop until you reach a consensus with more directions on QC choices
>> (and possibly new QC metrics as well), which you document in a painfully
>> detailed operations manual.
>> (5) Then you get an online interface were "naive" people who just read
>> the manual are presented with test cases to train and eventually certify
>> that people get it (when they reach a good-enough score).
>> (6) you grade intra-inter-rater consistency for naive raters that got
>> through the certification to check that it actually works.
>> (7) Finally, you test what is the effect of QC on a number of analysis,
>> to check if it does impact the results (and that it was worth doing all of
>> that).
>>
>> Frissoni, Duchesnes and coll. have done something like that for
>> hippocampus segmentation instead of QC, and I think this is a really good
>> way to help standardize the production of imaging outcomes. For the QC, the
>> same approach could work for a variety of packages, as NIAK/DSPARF/CPAC and
>> others have a lot of the operations in common, just using different tools.
>> Results of QC would actually be a great way to compare the
>> accuracy/robustness of different pipelines (one of the main things we have
>> examined so far is coregistration T1->stereotaxic and T1->BOLD).
>>
>> We have started working on this project with a PhD student, Yassine
>> Benhajali, in collaboration with some folks at NYU (Cameron Craddock, Chao
>> Gan Yang, Qingyang Li) as well as Maarten Mennes. This initiative started
>> at brainhack2012, and has been an important component of the "ABIDE
>> preprocessed" release (yet-to-come ... but getting there ...). Yassine has
>> drafted an operation manual that he is revising, and we have a number of
>> metrics that could be used in the first round of the panel. So we kind of
>> went through 1-4 once, and we should get a preliminary idea on 7 soon,
>> while preparing the "ABIDE preprocessed" paper.
>>
>> What we need to do next is to get an actual QC report form going (we just
>> agreed loosely on what to look at for now), ideally web-based, and update
>> the operation manual. And hopefully build the panel, select a dataset
>> (which is likely going to remain ABIDE ...) and go through one or more
>> iteration. If anybody is interested to be part of that, please get in
>> touch. I am going to post a project description on brainhack.org, but I
>> prefer to start first with an email on this list in case I get some good
>> feedback for the project description.
>>
>> Sorry about the long post. Best,
>>
>> Pierre
>>
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