GNU General Public License (GPL) Yes Weill Cornell Medical College NITRC Network Modification (NeMo) Tool Lite The NeMo Tool is the first that associates localized white matter (WM) lesions with disruptions in gray matter connectivity as a step toward understanding the lesions’ functional implications. A Tractogram Reference Set (TRS), i.e. collections of white matter fibers, is constructed from 73 normal healthy individuals and coregistered to a common space (MNI). The NeMo Tool uses the TRS to assess structural network disruption due to a particular WM lesion mask on a region and network-wise level. This tool is an easy way for researchers and clinicians to investigate changes in the structural brain network without having to perform tractography on their own normal data or on diseased/injured brains where the results may not represent the underlying physiology. Network Modification (NeMo) Tool Lite GNU General Public License (GPL), Computational Neuroscience http://www.nitrc.org/projects/brainnet_2013/, http://www.nitrc.org/projects/brainnet_2013/