Free For Non-Commercial Use Only Yes University of North Carolina at Chapel Hill NITRC MaCH-Admix Yes MaCH-Admix is an extension to MaCH for faster and more flexible imputaiton, especially in admixed populations. It has incorporated a novel piecewise reference selection method to create reference panels tailored for target individual(s). This reference selection method generates better imputation quality in shorter running time. MaCH-Admix also separates model parameter estimation from imputation. The separation allows users to perform imputation with standard reference panels + pre-calibrated parameters in a data independent fashion. Alternatively, if one works with study-specific reference panels, or isolated target population, one has the option to simultaneously estimate these model parameters while performing imputation. MaCH-Admix has included many other useful options and supports VCF input files. All existing MaCH documentation applies to MaCH-Admix. 2013-3-16 Beta version MaCH-Admix Domain Independent, Imaging Genomics, Free For Non-Commercial Use Only, Imputation, Depression, Attention Deficit Disorder with Hyperactivity, Alzheimer Disease, Crohn Disease http://www.nitrc.org/projects/mach-admix/, http://www.nitrc.org/projects/mach-admix/