Yes NITRC Vaa3D and Vaa3D-Neuron Windows Vista, Windows NT/2000, Linux, MacOS, Cygwin, Windows 95/98/2000, Windows XP Yes C++, C Xiaoxiao Liu Vaa3D (3D Visualization-Assisted Analysis) is a handy, fast, and versatile 3D/4D/5D Image Visualization & Analysis System for Bioimages & Surface Objects. Vaa3D is a cross-platform (Mac, Linux, and Windows) tool for visualizing large-scale (gigabytes, and 64-bit data) 3D/4D/5D image stacks and various surface data. It is also a container of powerful modules for 3D image analysis (cell segmentation, neuron tracing, brain registration, annotation, quantitative measurement and statistics, etc) and data management. Vaa3D is very easy to be extended via a powerful plugin interface. For example, many ITK tools are being converted to Vaa3D Plugins. Vaa3D-Neuron is built upon Vaa3D to make 3D neuron reconstruction much easier. In a recent Nature Biotechnology paper (2010, 28(4), pp.348-353) about Vaa3D and Vaa3D-Neuron, an order of magnitude of performance improvement (both reconstruction accuracy and speed) was achieved compared to other tools. 2016-6-23 5 - Production/Stable/Mature Vaa3D 3.2 2015-3-13 5 - Production/Stable/Mature Vaa3D-2.938 2010-6-24 5 - Production/Stable/Mature v2.475 2010-5-14 5 - Production/Stable/Mature V3D 2.466, V3D-Neuron 2.0, Plugin Interface 0.92 Vaa3D and Vaa3D-Neuron Image Display, Warping, Resampling, Algorithm or Reusable Library, Atlas Application, Neuronal Characterization, Surface Analysis, Position, Volumetric Analysis, Segmentation, Shape Analysis, Registration, Rendering, Fiber Tracking, Platform or Development Environment, 5 - Production/Stable/Mature, MR, Computational Neuroscience, Imaging Genomics, Win32 (MS Windows), KDE, Gnome, Other Environment, End Users, Other Audience, Developers, English, MacOS, Windows 95/98/2000, Windows XP, Windows Vista, Windows NT/2000, Linux, Cygwin, C, C++, Other Format, Depression, Parkinson Disease,