sdm-help-list > multiple meta-regression help
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May 3, 2017  07:05 PM | enrico vitolo
multiple meta-regression help
Dear SDM project Team,

I'm trying to run a multiple meta-regression with patients' mean age and illness duration as regressor to evaluate the effect of these parameters on altered brain regions. When i checked the output files, I found some files (html and nifti) named as "MyRegression_10", "10m", "11", and "12"..I can't understand what these files are..according to SDM manual, when i run a meta-regression, i obtain 3 type of maps: "regressor_1" (differences between patients with maximum regressor values and healthy controls), "regressor_0" (differences between patients with minimum regressor values and healthy controls), and "regressor_1m0" (differences between patients with maximum regressor values and patients with minimum YBOCS). I can't find any indication about other type of files/maps, nor about multiple meta-regression.
What type of file/maps are the files mentioned above?

Thank you very much for your precious help!

Best regards,
Enrico Vitolo
Jun 2, 2017  12:06 PM | Eunice Chen - Temple University
RE: multiple meta-regression help
Dear Enrico and Joaquim

Thank you Joaquim for making this program freely avaliable for use.
I think I have a similar problem to Enrico.

I want to check that I am interpreting multi metaregression results correctly.

So I have 2 regressors of interest. When I run the multi metaregression, I receive three outputs with these letters in the header.
01m00_z, 10m01_z and 10m00_z.
I want to check my understanding. Is this correct?
01m00_z = the effect of regressor 2, controlling for regressor 1
10m01_z = the effect of regressor 1, controlling for regressor 2
10m00_z = the effect of the interaction of regressor 1 and 2

If this isn't correct, I'd really appreciate the feedback.
Cheers, Eunice
Jun 2, 2017  02:06 PM | Joaquim Radua
RE: multiple meta-regression help
Dear Enrico and Eunice,

sorry for the confusing names of these maps, we hope that they will be less confusing in future versions of SDM.

When conducting a regression by two continuous variables:

- 10m00 is the effect of the first regressor

- 01m00 is the effect of the second regressor

Hope this helps,

Joaquim
Jun 2, 2017  02:06 PM | Eunice Chen - Temple University
RE: multiple meta-regression help
Ooh thank you.
To check what does the 10m01 denote?
Cheers, Eunice
Jun 2, 2017  02:06 PM | Joaquim Radua
RE: multiple meta-regression help
Dear Eunice,

I wouldn't use 10m01 in the context of a multiple regression. This is more useful in the context of an ANOVA.

Cheers,

Joaquim
Jun 2, 2017  02:06 PM | Eunice Chen - Temple University
RE: multiple meta-regression help
ok thank you!
Jun 2, 2017  05:06 PM | enrico vitolo
RE: multiple meta-regression help
Dear Joaquim,

thank you for your help!

Your answer is really helpful.

Best regards,

Enrico