open-discussion > Uncinate fasciculus
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Jan 24, 2019  01:01 PM | Benjamin Davidson
Uncinate fasciculus
HI there, 

Does anyone have a suggestion on how to map the uncinate fasciculus on DTI (single subject). I preprocessed our DTI images on FSL and am trying to use TrackVis to see the tracks. Although I can see the corpus callosum and corticospinal tracts nicely, I cannot seems to see the uncinate fasciculus despite using variously sized and positioned ROIs. 

Any help would be greatly appreciated!

Ben
Jan 24, 2019  01:01 PM | Martin Styner
RE: Uncinate fasciculus
Hi Ben
The uncinate should actually be fairly easy to track (though I am not too familiar with TrackVis, I do my tracking in Slicer). The problem is one of specificity, i.e. to place an ROI such that you only get the uncinate and nothing else is very difficult. I suggest you get a set of tracts first that includes the uncinate and then clean the tracks up afterwards (Slicer has a handy, interactive fiber selection/cleaning tool). For that, I usually place ROI either a) very generously in the anterior temporal lobe, or b) place an ROI is the up-down-ward region medial-anterior temporal lobe; if you look at the color coded FA image, you can see that as a small blue region in the medial & anterior temporal lobe. Option b is the most effective.
Hope this helps
Martin