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Notes:
The Brainnetome Project was launched to investigate the hierarchy
in the human brain from genetics to neuronal circuits to behaviors,
conceptualizing two components (nodes and connections) as the basic
research unit. One of the key prerequisites of this project is thus
to establish a new human brain atlas, i.e., the Brainnetome Atlas,
defining these nodes based on structural connectional architecture.
Using non-invasive multimodal neuroimaging techniques, we designed
a connectivity-based parcellation framework that identifies the
subdivisions of the entire human brain, revealing the in vivo
connectivity architecture. The resulting human Brainnetome Atlas,
with 210 cortical and 36 subcortical subregions, provides a
fine-grained, cross-validated atlas and contains information on
both anatomical and functional connections.. This new brain atlas
has the following four features: (A) It establishes a fine-grained
brain parcellation scheme for 210 cortical and 36 subcortical
regions with a coherent pattern of anatomical connections; (B) It
supplies a detailed map of anatomical and functional connections;
(C) it decodes brain functions using a meta-analytical approach;
and (D) It will be an open resource for researchers to use for the
analysis of whole brain parcellations, connections, and functions.
To facilitate future investigations in healthy and pathological
states, the atlas and accompanying software will be made freely
available for download at http://atlas.brainnetome.org.
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