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help > RE: tCompCor
Jan 16, 2015 02:01 AM | Alfonso Nieto-Castanon - Boston University
RE: tCompCor
Dear Daniele,
Unfortunately that is not in our near-future plans. The aCompCor approach allows us to explicitly define the "noise" voxels to lie within the White matter and CSF areas (while tCompCor will automatically identify those voxels for you but it does not guarantee that they will not lie within grey matter areas). In the context of functional connectivity analyses, potentially including grey-matter voxels into the CompCor computation can introduce, similar to global signal regression, artifactual biases (and in particular biases that could affect the proper interpretation of anticorrelations; see Murphy et al. 2009 "The impact of global signal regression on resting state correlations: Are anti-correlated networks introduced?"), so that is the main reasons why CONN has historically favored the aCompCor approach (and why implementing the tCompCor approach is not currently in our near-future plans, sorry about that)
Best
Alfonso
Originally posted by Daniele Mascali:
Unfortunately that is not in our near-future plans. The aCompCor approach allows us to explicitly define the "noise" voxels to lie within the White matter and CSF areas (while tCompCor will automatically identify those voxels for you but it does not guarantee that they will not lie within grey matter areas). In the context of functional connectivity analyses, potentially including grey-matter voxels into the CompCor computation can introduce, similar to global signal regression, artifactual biases (and in particular biases that could affect the proper interpretation of anticorrelations; see Murphy et al. 2009 "The impact of global signal regression on resting state correlations: Are anti-correlated networks introduced?"), so that is the main reasons why CONN has historically favored the aCompCor approach (and why implementing the tCompCor approach is not currently in our near-future plans, sorry about that)
Best
Alfonso
Originally posted by Daniele Mascali:
Dear all,
I know that in CONN is available the aCompCorr approach for noise mitigation.
I was wondering if you are going to implement also the tCompCor approach (as introduced in Behzadi 2007).
Thanks,
Daniele
I know that in CONN is available the aCompCorr approach for noise mitigation.
I was wondering if you are going to implement also the tCompCor approach (as introduced in Behzadi 2007).
Thanks,
Daniele
Threaded View
| Title | Author | Date |
|---|---|---|
| Daniele Mascali | Jan 15, 2015 | |
| Alfonso Nieto-Castanon | Jan 16, 2015 | |