[Dynamics of Brain Activity during Voluntary Movement: fMRI Study].

Zh Vyssh Nerv Deiat Im I P Pavlova. 2015 Jul-Aug;65(4):436-45

Authors: Sedov AS, Devetiarov DA, Semenova UN, Zavyalova VV, Ushakov VL, Medvednik RS, Ublinsky MV, Akhadov TA, Semenova NA

Abstract
The use of event-related fMRI makes it possible to investigate spatio-temporal dynamics of cortical and subcortical human brain structures activity during voluntary movement performance in response to presentation of relevant verbal stimuli. The results of the study showed that voluntary movement was associated with higher contralateral brain activation in a number of areas: primary motor and somatosensory cortex, premotor cortex, supplementary motor area and insula with adjacent regions. Ipsilateral activation of the cerebellum also was observed. It should be emphasized that contralateral strio-pallidal complex and ventral thalamus showed significant response to motor tasks. Similarly, the dynamics of cortex and deep brain structures activation involving in the phasic and tonic components of voluntary movement was uncovered. We showed, in particular, the noticeable difference in brain activation between the right and left hand movement performance. The obtained results enable to enhance understanding of the role of deep brain structures in voluntary movement organization in human and motor control system as a whole.

PMID: 26601503 [PubMed - in process]