What is NITRC?

Neuroimaging Informatics Tools and Resources Clearinghouse (NITRC) is currently a free one-stop-shop collaboratory for science researchers that need resources such as neuroimaging analysis software, publicly available data sets, or computing power. Since its debut in 2007, NITRC has helped the neuroscience community to use software and data produced from research that, before NITRC, was routinely lost or disregarded, to make further discoveries. NITRC provides free access to data and enables pay-per-use cloud-based access to unlimited computing power, enabling worldwide scientific collaboration with minimal startup and cost. With NITRC and its components—the Resources Registry (NITRC-R), Image Repository (NITRC-IR), and Computational Environment (NITRC-CE)—a researcher can obtain pilot or proof-of-concept data to validate a hypothesis for a few dollars.

NITRC scientific focus includes: PET/SPECT, CT, EEG/MEG, optical imaging, clinical neuroinformatics, computational neuroscience, and imaging genomics software tools, data, and computational resources.


NITRC Resources Registry (NITRC-R) promotes software tools and resources, vocabularies, test data, and databases, thereby extending the impact of previously funded, neuroimaging informatics contributions to a broader community. NITRC-R gives researchers greater and more efficient access to the tools and resources they need, better categorizing and organizing existing tools and resources, facilitating interactions between researchers and developers, and promoting better use through enhanced documentation and tutorials—all while directing the most recent upgrades, forums, and updates.


NITRC Image Repository (NITRC-IR) does for data what NITRC-R does for tools. Search for and freely download publicly available data sets including thousands of DICOM and NIFTI normal subjects and those with diagnoses such as: schizophrenia, ADHD, autism, and Parkinson's.


NITRC Computational Environment (NITRC-CE) is a freely downloadable, or pay-as-you-go virtual computing cloud-based platform pre-configured with popular neuroimaging software tools such as AFNI, ANTS, FreeSurfer, FSL and more. You may use any of these pre-installed tools to analyze your data more quickly and more easily than having to configure them all on your own; better to spend your time on research than on system configuration and administration. And, if our pre-installed selections are not sufficient, you can add your own commercial and open source software tools to your virtual machine.

Join Us!

As this is community driven collaboratory, NITRC needs you to make it an even more efficient, trustworthy on-line community for discussion and collaboration regarding neuroimaging informatics analysis tools and resources.

To fully participate, consider becoming a registered NITRC user. Everyone would benefit from your contributions, via our forums, shared documents, wiki, and especially the tool/resource ratings and reviews—researchers new to neuroimaging analysis need community input about the tools/resources that might best suit their research.

We're Award Winning

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In 2015, NITRC was recognized by the Department of Health and Human Services as the project to have given the "Biggest Bang for the Buck" for providing "significant savings or return-on-investment for HHS resources expended," the NIH award submission noted that the project has delivered "a potential cost avoidance of over $35.3 million."

NITRC was one of seven Innovation awardees, and was chosen out of over 70 applicants. In addition, in 2009 NITRC was awarded "Best Overall" category Excellence.Gov.

How are we Funded?

NITRC is funded by: NIH Blueprint for Neuroscience Research, National Institute of Biomedical Imaging and Bioengineering, National Institute of Drug Addiction, National Institute of Mental Health, and National Institute of Neurological Disorders and Stroke.

About the NITRC Team

NITRC is being built and operated by TCG, Inc. of Washington, D.C. in collaboration with University of Massachusetts Medical School of Worcester, MA; Neuromorphometrics of Somerville, MA; and is hosted by the Center for Research in Biological Systems of the University of California, San Diego.

NITRC's project management and development team consists of Nina Preuss, PmP, Robert Buccigrossi, Ph.D., Matthew Travers, Albert Crowley, Abby Carr, David Kirkpatrick, Natalie Graeff, and formerly, Haig Evans-Kavaldjian, Kimberly Pohland, Kent Reynolds, Maureen Sullivan, and Judith Turner, PmP.

TCG, Inc.: At TCG, we pride ourselves on being and thinking differently—and we apply this approach to everything we do. As a result, we develop unique solutions that change the way government works.

For more than 20 years, TCG has helped federal agencies develop custom-built solutions tailored to meet their exact requirements. We're smart, fair, honest, and open and we invest in every challenge put before us. We help government improve while saving time and money. For more information, contact David Cassidy at david.cassidy@tcg.com.

University of Massachusetts Medical School

The NITRC Community Liaison is David N. Kennedy, Ph.D., Director of the Division of Neuroinformatics at the Child and Adolescent Neurodevelpment Initiative (CANDI) and Professor of Psychiatry at the University of Massachusetts Medical School. He has extensive expertise in the development of image analysis techniques and was a co-founder of the Center for Morphometric Analysis (CMA) at Massachusetts General Hospital. In addition, David is a founding editor of the journal Neuroinformatics. For more information, contact David Kennedy at david.kennedy@umassmed.edu.

Neuromorphometrics, Inc.

Neuromorphometrics, Inc. addresses the need for a service to obtain quantitative brain measurements using MRI. Neuromorphometrics provides Christian Haselgrove, the NITRC Moderator and Site Administrator, who has been Chief Neuroinformatics Officer of Neuromorphometrics since 2006. While the major component of his work at Neuromorphometrics is NITRC, past and continuing work includes designing, building, and running the Internet Analysis Tools Registry at the Massachusetts General Hospital and serving on the NIfTI Data Format Working Group since its formation. Nueromorphometrics also provides the following domain curators: Giorgio Ascoili, Ph.D, Arnaud Delorme, Ph.D., Karl Helmer, Ph.D., Steven Bressler, Ph.D., Li Shen, Ph.D., and formerly, David Boas, Ph.D. and Randy Gollub, Ph.D. For more information about Neuromorphometrics, see Andrew Worth at http://neuromorphometrics.com/.

UCSD Center for Research in Biological Systems

The NITRC website and NITRC Image Repository are hosted by the Center for Research in Biological Systems (CRBS; http://crbs.ucsd.edu), an organized research unit at UCSD, which facilitates an interdisciplinary infrastructure in which people from biology, medicine, chemistry, and physics can work with those from computer science and information technologies in collaborative research. Leading the CRBS team hosting NITRC is Dr. Jeffrey Grethe. CRBS researchers have been at the forefront of neuroinformatics with involvement in NSF's National Partnership for Advanced Computational Infrastructure, one of the first projects to provide an advanced cyber-infrastructure for the scientific community, to playing a key role in the building of the Biomedical Informatics Research Network and the National Database for Autism Research, and to many high profile informatics projects such as the Neuroscience Information Framework (NIF; http://neuinfo.org), the NIDDK Information Network (dkNET; http://dknet.org), and the Research Resource Identification Initiative (https://scicrunch.org/resources). CRBS consists of a unique and well-established partnership between computer scientists, biomedical scientists, and engineers whose application of information technologies is accelerating the pace of discovery in health research.