Hi Ehsan,

I apologize for the long processing times. Hopefully we will continue to improve the computational efficiency of DKE in the future. Right now we're limited because the source code is written in Matlab. I have gotten the processing times down to around 10 mins for many of my datasets, but this is both platform and dataset specific.

I would disregard the second error. In computation of the kurtosis dODF, the diffusion tensor must be inverted, and this error occurs when the diffusion tensor is degenerate, which may occur in the image background and periphery of the image where the diffusion signal is largely noise. This should not happen within the brain volume.

I am unsure what the cause of your first error could be. This could occur as the result of a permissions error in your local environment but I doubt this is the case. I am happy to take a look at your data if you like and see if I can diagnose this further. If this is ok with you you could upload the DT.mat, KT.mat, and fa.nii files somewhere? These files are fully anonymized and contain no identifiable info. Just an option...

Best,

Russell