|
Notes:
#####################
## v1_Beta_20141216
#####################
This is a multi-mode (T1w and DTI) brain template of monkeys during
late infancy (from 6 months of age to 16 months of age, postnatal),
which will help spatial normalization, voxel-based and tract-based
analyses in non-human primates.
Lots efforts were made to ensure their quality:
1) we manually skull-striped brains for all MRI&DTI data (120+
brains in total). The time-consuming procedure guaranteed more
accurate brain extraction than automatic methods (3dSkullStrip or
BET).
2) We had tested different spatial normalization tools, and the
best ones were chosen to build the MRI (by ANTS) and DTI (by
DTI-TK) templates.
3) We also made the high quality template-related files, including
parcellation maps, tissue probability maps, inferior cingulum mask
for the TBSS, and template for each time points.
Detailed information about monkeys and methods for building
template can be found in:
Liu,C, et al. "Rhesus monkey brain development during late infancy
and the effect of phencyclidine: a longitudinal MRI and DTI study."
NeuroImage (2015).
http://www.ncbi.nlm.nih.gov/pubmed/25485...
Funding supports:
Financial support for the data used in this project was from 973
program (2012CB825500, 2011CB707800), NSFC (31271168, 91132307/H09,
61178051) and NSFC Finnish-Chinese joint project 813111172.
For questions contact Cirong Liu (cirongliu@gmail.com ) or Jianhong Wang (wjh16@hotmail.com)
#####################
## File descriptions
#####################
All_S6toS16_* --> These templates were builded based all scans
(all monkeys and all time points) from 6 months of ages to 16
months. They are good representations for monkey brains during late
infancy, and recommanded to used.
S* --> These templates were builded based scans from one
particular time point. Note that S7 and S8 only had 10 monkeys
scanned, while the S6, S10 and S16 had all 14 monkeys scanned.
parcellation_lables AND subcortical_lables --> These
parcellation maps were derived from UNC Primate Brain Atlas.
Several modifications were made, including manually subdividing the
PFC into dosal PFC and ventral PFC.
All_S6toS16_ANTS_T1w_laplaciansharpen --> A version of T1w
templates by applying a laplacian sharpening to the standard
average, which highlighted regions of rapid intensity change and
can enhance the contrast of boundaries between different tissues if
images were well-aligned.
*_pCSF, *_pGM, *_WM --> tissue probability maps
*_DTITK_DTI_searchmask --> An inferior cingulum mask was
manually drawn on the template space to facilitate FA projection of
TBSS analysis because the inferior cingulum tract had no
well-defined search direction for the projection due to its tubular
skeleton topology. Note that the mask were drawn on the template of
all scans, and transformed to templates of a particular time point.
Changes:
|
