help > RE: Movement
Nov 19, 2014  06:11 AM | Alfonso Nieto-Castanon - Boston University
RE: Movement
Hi Brad,

Yes, having a large proportion of the BOLD signal variance explained by the combination of confounding effects is perfectly normal/expected (motion and physiological effects can be very large compared to the neural sources in the BOLD signal).

Also you are right that the interpretation of the percentage variance explained by each confounding effect was a bit counter-intuitive (this has also been changed in more recent versions). In older versions the effects shown in these Denoising plots represented the "unique variance" explained by each factor (the total variance explained by that factor alone, after removing all that could be explained by the other factors), while in newer versions this plot has been changed to represent the "unique&shared variance" explained by each factor (the total variance explained by that factor, even if some portion of that variance would also be explained by other factors). The combination/addition of the "unique variance" of several factors is always smaller that the total variance explained by all factors combined, and the combination of the "unique&shared variance" of several factors is always larger than the total variance explained by all factors combined (and we were hoping that using the latter would perhaps make it a bit more intuitive interpreting these plots). 

Hope this helps
Alfonso
Originally posted by Bradley Taber-Thomas:
Great, thanks, the new version works as you described.

A lot of subjects have their "TOTAL Confounds" explaining most of the variance, as in the screen shot attached to that previous post. Does that look normal to you? The Total doesn't seem to be a combination of the individual confounds, and it is certainly a lot of the variance (e.g., for some subjects the Total confounds explain >0.9 variance for the whole brain).

Best,
Brad

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TitleAuthorDate
Kaylah Curtis Jul 23, 2014
Mary Newsome Apr 2, 2015
Alfonso Nieto-Castanon Apr 6, 2015
Alfonso Nieto-Castanon Jul 29, 2014
Xiaozhen You Mar 31, 2015
Fred Uquillas Mar 31, 2015
Xiaozhen You Apr 1, 2015
Fred Uquillas Apr 1, 2015
Alfonso Nieto-Castanon Apr 2, 2015
Xiaozhen You Apr 2, 2015
Ekaterina Shcheglova Mar 26, 2023
Fred Uquillas Apr 24, 2015
Alfonso Nieto-Castanon Apr 28, 2015
Fred Uquillas May 6, 2015
Arkan A May 6, 2015
Alfonso Nieto-Castanon May 6, 2015
Arkan A May 7, 2015
Alfonso Nieto-Castanon May 8, 2015
Arkan A May 8, 2015
Bradley Taber-Thomas Sep 30, 2014
Alfonso Nieto-Castanon Oct 1, 2014
Bradley Taber-Thomas Oct 1, 2014
RE: Movement
Alfonso Nieto-Castanon Nov 19, 2014
Kaylah Curtis Jul 29, 2014
Alfonso Nieto-Castanon Jul 30, 2014
Alexander Drobyshevsky Oct 21, 2014
Alfonso Nieto-Castanon Nov 19, 2014
Kaylah Curtis Jul 30, 2014
Aleksandra Herman Oct 23, 2014