help
help > RE: Corpus Callosum Segmentation Information?
Dec 16, 2013 08:12 PM | Babak Ardekani
RE: Corpus Callosum Segmentation Information?
Originally posted by Keerthana Karunakaran:
Hi,
Yes, although there is no guarantee that the tracts that go through point #87 on both subjects connect the same cortical regions in both subject, there is a good chance that they do because in both subjects the distance from the inferior point of the splenium to the 87th point equal 87% of the total length of their medial axes.
So this method assumes that for example the isthmus of the CC in different subjects is located at approximately the same location along the length of the CC if the length is normalized to 1.
When you plot the thickness profiles for multiple subjects, you will see that they more or less have the same pattern which supports the above model.
However, there will be cases that this assumption will not hold so this method is only good for comparing groups.
Babak
Babak Ardekani,
Thank you very much for your response. I have one more question.
If CC length of subject 1 is 'X' cm and subject 2 is 'Y' cm and Y>X. After 100 thickness points are obtained, when i want to compare thickness point 87 of X with point 87 of Y. I may not be looking at the same region of the brain that particular point of CC is linked to.
For example point 87 in CC of Y might include prefrontal and mid frontal gyrus, where as 87 in CC of X might only include prefrontal gyrus because of smaller CC length and segment area.
This is where I am having problem understanding. I would very much appreciate it if you could please help.
Thank you once again.
Regards,
Keerthana
Thank you very much for your response. I have one more question.
If CC length of subject 1 is 'X' cm and subject 2 is 'Y' cm and Y>X. After 100 thickness points are obtained, when i want to compare thickness point 87 of X with point 87 of Y. I may not be looking at the same region of the brain that particular point of CC is linked to.
For example point 87 in CC of Y might include prefrontal and mid frontal gyrus, where as 87 in CC of X might only include prefrontal gyrus because of smaller CC length and segment area.
This is where I am having problem understanding. I would very much appreciate it if you could please help.
Thank you once again.
Regards,
Keerthana
Hi,
Yes, although there is no guarantee that the tracts that go through point #87 on both subjects connect the same cortical regions in both subject, there is a good chance that they do because in both subjects the distance from the inferior point of the splenium to the 87th point equal 87% of the total length of their medial axes.
So this method assumes that for example the isthmus of the CC in different subjects is located at approximately the same location along the length of the CC if the length is normalized to 1.
When you plot the thickness profiles for multiple subjects, you will see that they more or less have the same pattern which supports the above model.
However, there will be cases that this assumption will not hold so this method is only good for comparing groups.
Babak
Threaded View
| Title | Author | Date |
|---|---|---|
| Timothy Herron | Apr 16, 2012 | |
| Babak Ardekani | Apr 17, 2012 | |
| Samuel SARRAZIN | Nov 18, 2013 | |
| Babak Ardekani | Nov 18, 2013 | |
| Samuel SARRAZIN | Nov 19, 2013 | |
| Keerthana Karunakaran | Dec 16, 2013 | |
| Babak Ardekani | Dec 16, 2013 | |
| Keerthana Karunakaran | Dec 16, 2013 | |
| Babak Ardekani | Dec 16, 2013 | |
| Samuel SARRAZIN | Jun 9, 2013 | |
| Babak Ardekani | Jun 11, 2013 | |
| Babak Ardekani | Jan 12, 2013 | |
| Dianne Patterson | Sep 25, 2013 | |
| Babak Ardekani | Sep 25, 2013 | |