Release Name: SchitzBull_Atlas_V1.0


Introducing CANDIShare  Schiz_Bull_2008 Atlases Version 1.0.  This is the initial set of atlases generated from the image and segmentation results released for the Skitzphrenia Bullitin article.


It is based upon MRI images and
segmentation results of all 4 diagnostic groups (Healthy Controls
(N=29), Schizophrenia Spectrum (N=20), Bipolar Disorder with Psychosis
(N=19), and Bipolar Disorder without Psychosis (N=35)) from the article:
Frazier JA, Hodge SM, Breeze JL, Giuliano AJ, Terry JE, Moore CM,
Kennedy DN, Lopez-Larson MP, Caviness  VS, Seidman LJ, Zablotsky B,
Makris N. Diagnostic and sex effects on  limbic volumes in early-onset
bipolar disorder and schizophrenia.  Schizophr Bull. 2008

The release contains a zipped tar file of the CANDI Atlases directory.  Within this directory will be atlases for multiple studies/publications.  In this case, the SchitzBull_2008 subdiretory is found. Since an atlas can be made using many different methods, we expect to see a different subdirectory for each different atlasing method. This first release is named Affine_2_MNI152_2mm as it uses linear, affine transformation (fsl flirt) to the MNI152_2mm target brain. Within this atlas subdirectory, we find the subdirectories for the 4 subgropus (HC, SS, BPDwithPsy & BPDwithoutPsy).


Each of these atlas subdirectories includes a $DIAG_STRS subdirectory which contains a probbility file for each of the individual anatomc structures. These probability files are of the type nii.gz and are in the range of [0,1] representing the probability of the given structure (XX) in the diagnostic population. The stucture codes are as provided in 'seg_fill_values.txt' file to
be found in the Documents section of the CANDIShare NITRC project.  The
fill values are correct for automatic interpretation using the 'CMA
Subcortical' color pallet in fslview and the Freesurfer


In addition, the diagnostic directory contains a $DIAG_pMAX.nii.gz file which, in target (MNI152_2mm) spave has the maximum p value of any structure for each voxel. Also found is the $DIAG_pSEG.nii.gz which contains the label value for the sucture of the maximum probability at each voxel location.


Soon, we will release the detailed processing script that generated these results.