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Notes:
This is an atlas set that can be used with ASHS-FAST VERSION 2.0
(July 2018) OR LATER software to perform automatic segmentation of
medial temporal lobe substructures in 3 Tesla T1-weighted MRI
(MPRAGE) scans explicitly accounting for the dura mater (which has
similar intensity as gray matter in T1-weighted MRI that could
confound automatic segmentation).
This atlas set was constructed from MRI scans acquired in research
studies conducted at the Penn Memory Center at the University of
Pennsylvania by David A. Wolk, Paul A. Yushkevich and colleagues.
The scans have been segmented
manually by Long Xie and Laura Wisse based on the manual
segmentations in the Penn Memory Center 3T ASHS Atlas for
T2-weighted MRI (by John Pluta).
The atlas contains segmented scans of 29 older adults, 14 meeting
the Peterson criteria for amnestic mild cognitive impairment, and
15 controls. Scans were acquired at 3 Tesla. The whole brain
T1-weighted scans are at 1.0x1.0x1.0 mm3 resolution. The labels
include anterior/posterior hippocampus, entorhinal cortex (ERC),
perirhinal cortex (further divided into Brodmann areas 35 and 36,
or BA35 and BA36), and parahippocampal cortex (PHC).
Any use in publication should cite
XieL., WisseE.M.L., ManjonV.J. Wang H., Das, S.R., Wolk A.D.,
Yushkevich A.P. (2016). Accounting for the Confound of Meninges in
Segmenting Entorhinal and Perirhinal Cortices in T1-weighted MRI.
Athens, Greece. Medical Image Computing and Computer-Assisted
Intervention–MICCAI 2016(pp. 564-571). Springer International
Publishing.
Please see these papers for details on the dataset.
Changes:
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