EMSE Suite is a professionally supported three-tier platform for space-time-frequency analyses of EEG/MEG/ECoG integrated (optionally) with structural MRI. Locator 2 efficiently digitizes 3D sensor coordinates. TIER 1: Data Editor+ with 3D mapping provides live and offline pipelines of spatial and temporal filters, with easy-to-use event pipelines for conditional binning of time, frequency, and time-frequency data (including connectivity measures) across participants, with group results. TIER 2: EMSE Source Standard provides standard finite element method (FEM) head models for inverse estimation of discrete overdetermined and distributed underdetermined sources, including spatial filtering for 3D brain ROIs. Statistical nonparametric mapping (SnPM) is available for all measures. TIER 3: EMSE Source MRI creates MRI-based individual FEM volume conductor models and cortical source space models. See https://cortechsolutions.com/EMSE/ for details and a supported free trial.