TRENTOOL (TRansfer ENtropy TOOLbox) is an open source GPLv3 Matlab® toolbox for the analysis of information transfer in time series data.

Transfer entropy (TE) is an information-theoretic measure of directed information transfer; it offers an approach to the detection of neuronal interactions that is free of an explicit model of the interactions and thus offers the power to analyze linear and nonlinear interactions alike.

TRENTOOL provides user friendly routines for the estimation and statistical testing of TE in time series data. For the use with neural data TRENTOOL seamlessly integrates with the popular FieldTrip toolbox.