open-discussion
open-discussion > RE: Spatial Smoothing before vs. after Compcor
Aug 3, 2015 05:08 PM | Alfonso Nieto-Castanon - Boston University
RE: Spatial Smoothing before vs. after Compcor
Hi Andrew,
See this post (https://www.nitrc.org/forum/message.php?...) for a related discussion. Briefly, that should be fine, the main concern will be to make sure that the White/CSF signals used by aCompCor do not include spillage from gray matter areas due to spatial smoothing so I would suggest to use conservative White/CSF masks to minimize this risk, e.g. erode these masks before extracting White/CSF BOLD signals (if using CONN this erosion is performed automatically as part of the default processing steps)
Hope this helps
Alfonso
Originally posted by Andrew Song:
See this post (https://www.nitrc.org/forum/message.php?...) for a related discussion. Briefly, that should be fine, the main concern will be to make sure that the White/CSF signals used by aCompCor do not include spillage from gray matter areas due to spatial smoothing so I would suggest to use conservative White/CSF masks to minimize this risk, e.g. erode these masks before extracting White/CSF BOLD signals (if using CONN this erosion is performed automatically as part of the default processing steps)
Hope this helps
Alfonso
Originally posted by Andrew Song:
Hi Alfonso,
Thank you very much for the insight. It indeed makes sense.
What if, and this is my current situation, I only have access to already-smoothed data and thus can only run CompCor on this modified data?
Would there be noticeable performance degradation when compared to the approach stated in your reply?
Thanks again,
Thank you very much for the insight. It indeed makes sense.
What if, and this is my current situation, I only have access to already-smoothed data and thus can only run CompCor on this modified data?
Would there be noticeable performance degradation when compared to the approach stated in your reply?
Thanks again,
Threaded View
| Title | Author | Date |
|---|---|---|
| Andrew Song | Jul 30, 2015 | |
| Alfonso Nieto-Castanon | Jul 31, 2015 | |
| Andrew Song | Jul 31, 2015 | |
| Alfonso Nieto-Castanon | Aug 3, 2015 | |