help > RE: WMH Map Output
Dec 3, 2015  07:12 AM | Vamsi Ithapu
RE: WMH Map Output
Hello.
Pardon me, I understood your question incorrectly!
You are right in the semse that the _pmap_ does give the final hyperintense regions.
Because of the higher overall brightness of the tissues, the algorithm is picking up most of the white matter as relevant for hyperintense regions of interest. Further, _pamp_ is a probability map i.e, each voxel corresponds to a signal between 0 and 1 representing how strong the corresponding voxel is interms of being classified as a hyperintensity. Hence, we see the very bright regions along with slightly darker ones (in the ex image you have attached here with).

The solution is still to play around with the preprocessing and quantification hyper-paramters. Changing the bias correction level and smoothing factors in the SPM preprocessing pipeline (refer WHyD_preproc.m) would also be relevant.
Further, changing the pmap_cut and clean_th for quantification would help neglect the darker regions on the _pmap_ image (i.e., while computing EV values the low probable darker regions on _pmap_, which ideally popped up because of the issue of overall brightness being high, will not be used). Please refer to the documentation.

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TitleAuthorDate
John Morris Nov 20, 2015
Thiago Maciel Mar 19, 2016
Vamsi Ithapu Mar 20, 2016
John Morris Mar 19, 2016
Thiago Maciel Mar 19, 2016
Vamsi Ithapu Mar 20, 2016
John Morris Dec 13, 2015
RE: WMH Map Output
Vamsi Ithapu Dec 3, 2015
Dan Liu Dec 4, 2015
Vamsi Ithapu Dec 6, 2015
Dan Liu Jan 14, 2016
Vamsi Ithapu Jan 19, 2016
Dan Liu Feb 23, 2016
Dan Liu Feb 5, 2016
Dan Liu Dec 7, 2015
Vamsi Ithapu Dec 3, 2015