Longitudinal neuroimaging hippocampal markers for diagnosing Alzheimer's disease

Longitudinal framework for joint hippocampal segmentation and marker extraction from brain MRI at multiple time points. Combines 4D graph cuts with longitudinal atrophy constraints, discriminative appearance modelling (k-NN + filter-bank features), and non-rigid atlas registration (15 atlases, Elastix). Outputs: hippocampal volume and surface roughness per time point. Language: MATLAB R2017b (MEX win64). Related paper: Platero C., Lin L., Tobar M.C., Neuroinformatics 2019. DOI: 10.1007/s12021-018-9380-2. PMID: 29785624RRID: SCR_016282. Permanent archive: https://doi.org/10.5281/zenodo.19819265

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