I just want to clarify something. If we’re using the aggressive denoising strategy on the _desc-preproc_bold.nii.gz data, do we also need to include the motion parameters (trans_x trans_y trans_z rot_x rot_y rot_z) in our nuisance regression, or will they already be regressed out by the ICA-AROMA confounds?

I realize that we would want to include these motion parameters in a nuisance regression if we were just using the _desc-preproc_bold.nii.gz data without ICA-AROMA denoising; however, does it make sense to include them with _desc-preproc_bold.nii.gz + aggressive ICA-AROMA confounds, (or even for analyzing the non-aggressive smoothAROMAnonaggr_bold.nii.gz data?).

Thanks for the clarification.