BBIR Release of R56-NS055951-v01Posted By: Aaron Carass - Mar 4, 2020
Tool/Resource: Brain Biomechanics Imaging Resources
The Brain Biomechanics Imaging Resources makes available six data sets that provide 3D estimates over time of how the in-vivo, human brain deforms in response to measured mild accelerative loading of the skull during neck rotation (N=3) and neck extension (N=3). The data were obtained using tagged magnetic resonance imaging (MRI). An MRI-compatible motion position sensor was used to record the loading conditions during the impact event. Estimates of full-field brain-skull displacement and Lagrangian strain were estimated using the harmonic phase finite element method. In order to relate brain deformation to subject-specific brain structure, additional anatomical MRI data were acquired and rigidly aligned to the measurements of brain deformation to enable characterization of anatomical structures, and the orientation of white matter fibers. These data sets are a unique resource for researchers interested in evaluating and calibrating computational models of traumatic brain injury using in vivo experimental data. Additionally, the anatomical MRI data can be used to create subject-specific computational models, which can then be directly compared to the provided measurements of brain deformation.