Dear Proffesor, i followed your recomendations and some of the patients showed connectivity differences.
Now i will try to compare both groups as a hole, but would like to have your advice on how to incorporate a clinical variable for a correlation analysis and how the contrast should be defined.
For instance, i have this design and wants to run a t- test
0 1
0 1
0 1
1 0
1 0
1 0

Will be ok to add a new column directly with the clinical values for each datapoint ? And then how can the contrast be defined ?

Thanks again for your time and help
Juan