help > repeat measures, multiple group comparison
Aug 19, 2017  01:08 PM | Jaykumar Grandhi - Cleveland Clinic Foundation
repeat measures, multiple group comparison

Hello!
Thanks for designing this helpful program.  I asked a question earlier and got some very helpful feedback, so thank you for that as well 
I need some help with preparing the DM, blocks, and contrast for 2 study paradigms. 
My study contains:
 90 subjects, 3 groups (or 2 groups, depending on hypothesis tested), and 2 measures.

Demonstrating using 3 subjects to save space, the following design has been working beautifully to show a difference between the measures(t-test):
_______________________________________________________
                time1 = 1  
        const   time2 =-1
  
subj1     1        1  
subj2     1        1    
subj3     1        1    
subj1     1       -1   
subj2     1       -1    
subj3     1       -1   
       
contrast  0       1  
      
exchangeblocks 1  2  3  1  2  3
_______________________________________________________

Now I need to compare the (time1-time2) repeated measures from group 1 to group (2 or 3), and additionally to compare all three.  Will the following work?

1. Repeated measures, comparing (group 1 - group 2): t-test.

_______________________________________________________
                     time1 = 1    group1
          const      time2 =-1    group(2or3)
 
subj1       1           1           1   
subj2       1           1           1   
subj3       1           1          -2   
subj1       1          -1           1   
subj2       1          -1           1   
subj3       1          -1          -2   
      
contrast    0           0           1   
      
exchangeblocks 1  2  3  1  2  3
_______________________________________________________
 
2. Repeated measures, (group 1 = group 2 = group 3): f-test
 
_______________________________________________________
                    time1 = 1  group1  group2  
          const     time2 =-1  group3  group3  
subj1       1           1         1       0  
subj2       1           1         0       1  
subj3       1           1         0       0  
subj1       1          -1         1       0  
subj2       1          -1         0       1  
subj3       1          -1         0       0  
      
contrast    0           0         1       1  
        
exchangeblocks 1  2  3  1  2  3
_______________________________________________________

Thanks so much for the help!

Jay

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TitleAuthorDate
repeat measures, multiple group comparison
Jaykumar Grandhi Aug 19, 2017
Andrew Zalesky Aug 21, 2017
Jaykumar Grandhi Aug 22, 2017
Andrew Zalesky Aug 23, 2017
Jaykumar Grandhi Sep 5, 2017
Andrew Zalesky Sep 6, 2017
Jaykumar Grandhi Aug 23, 2017
Andrew Zalesky Aug 23, 2017