Hi,

I have probably a trivial question but I just want to be sure.

I have rfMRI data from 19 subjects before and after treatment as well as one cognitive test parameters.

To know the difference between my two sessions, I realized a paired t-test.
To find correlation with my test parameters I made a 3 columns design ( one, age, parameter) with a design [0,0,1] or [0,0,-1]

Now I would like to see the improvement between my two sessions and so maybe see a correlation with the difference between run1 and run2 of my test parameters..... but statistically, am I allowed to subtract correlation matrices? (I mean I am planning to fisher transform them but is it right?)

Thanks a lot for your help

Cc