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help > RE: Design matrix not found or inconsistent error
Feb 12, 2021 11:02 PM | Andrew Zalesky
RE: Design matrix not found or inconsistent error
Hi Jean,
the design matrix and contrasts appear correct.
It may simply be that there is no association with the clinical variable, or you need a larger sample size to detect any potential association.
You could increase alpha to 0.1, to get a sense for this, but I would not put much credibility into findings found at alpha=0.1.
Andrew
Originally posted by YaeJi Kim:
the design matrix and contrasts appear correct.
It may simply be that there is no association with the clinical variable, or you need a larger sample size to detect any potential association.
You could increase alpha to 0.1, to get a sense for this, but I would not put much credibility into findings found at alpha=0.1.
Andrew
Originally posted by YaeJi Kim:
Dear Andrew,
Thank you for the advice. I reviewed my connectivity matrices, and I found one matrix was invalid.
I ran a correlational analysis in a single group to find the subnetwork reflecting correlational relationship associated with the clinical variable.
However, I couldn't find any significant result, so I am not sure my design matrix and contrast are correct.
My design matrix is as follows:
1 0.6
1 -0.4
1 -1.5
1 0.2
1 -0.7
. .
. .
. .
so on..
which first column indicates global mean and second column indicates the clinical variable.
I set my contrast as [0 1] for positive correlation, and [0 -1] for negative.
I ran t-test and set t-threshold ranged from 1.0~3.0.
Is this design and analysis correct for my hypothesis?
Sicnerely,
Jean
Thank you for the advice. I reviewed my connectivity matrices, and I found one matrix was invalid.
I ran a correlational analysis in a single group to find the subnetwork reflecting correlational relationship associated with the clinical variable.
However, I couldn't find any significant result, so I am not sure my design matrix and contrast are correct.
My design matrix is as follows:
1 0.6
1 -0.4
1 -1.5
1 0.2
1 -0.7
. .
. .
. .
so on..
which first column indicates global mean and second column indicates the clinical variable.
I set my contrast as [0 1] for positive correlation, and [0 -1] for negative.
I ran t-test and set t-threshold ranged from 1.0~3.0.
Is this design and analysis correct for my hypothesis?
Sicnerely,
Jean
Threaded View
| Title | Author | Date |
|---|---|---|
| YaeJi Kim | Feb 10, 2021 | |
| Andrew Zalesky | Feb 11, 2021 | |
| YaeJi Kim | Feb 12, 2021 | |
| Andrew Zalesky | Feb 12, 2021 | |