help > Question about the interpretation of "significant clusters"
Apr 13, 2023  01:04 PM | willhedley
Question about the interpretation of "significant clusters"
So I got into a discussion recently about the interpretation of "significant clusters" when using NBS toolbox.

I have always considered this advice from Fieldtrip when interpreting them: https://www.fieldtriptoolbox.org/faq/how... (which has functions for non-parametric cluster statistics but for clusters in time and space using MEG instead of clusters in connectivity matrices - but I think the principle is the same regarding how the permutations are performed) - this says we cannot say too much about the actual size and extent of a significant cluster. With this interpretation, all that can be said from the statistical test is that there is a significant difference between the connectivity matrices of two groups after rejecting the null hypothesis which is "there is no difference between the connectivity matrices between two groups".

However, a lot of articles using NBS don't seem to take this advice and interpret their "significant cluster" in quite a lot of detail (e.g. interpreting the size as significant and the exact cluster of significant edges in quite some detail). Is there any reason I am missing why the fieldtrip advice does not equally apply for NBS as well?

Thanks in advance!

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TitleAuthorDate
Question about the interpretation of "significant clusters"
willhedley Apr 13, 2023
Andrew Zalesky Apr 14, 2023