An in vivo 7T Probabilistic Atlas of the Human Locus Coeruleus

The 7T probabilistic LC atlas is created using magnetisation transfer images from 53 healthy volunteers (52 - 84 years) with ultra-high field 7T MRI. The atlas benefits from improved spatial resolution (0.4 x 0.4 x 0.5 mm) and SNR at 7T, advanced registration and segmentation methods, and consistent spatial features comparing to ex vivo findings.

The details for building the atlas and its derived images are described in: Rong Ye, Catarina Rua, Claire O'Callaghan, P Simon Jones, Frank Hubert Hezemans, Sanne S Kaalund, Kamen A Tsvetanov, Christopher Rodgers, Guy Williams, Luca Passamonti, James Rowe; An in vivo Probabilistic Atlas of the Human Locus Coeruleus at Ultra-high Field; bioRxiv 2020.02.03.932087; doi: https://doi.org/10.1101/2020.02.03.93208...

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MR