Microstructure Imaging Sequence Simulation Toolbox (MISST), is a practical diffusion MRI simulator for development, testing, and optimisation of novel MR pulse sequences for microstructure imaging. MISST is based on a matrix method approach and simulates the signal for a large variety of pulse sequences and tissue models. Its key purpose is to provide a deep understanding of the restricted diffusion MRI signal for a wide range of realistic, fully flexible, scanner acquisition protocols, in practical computational time.
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The Artistic License is intended to allow a package to be released as open source while still giving the originator some control over the future of the package. The Artistic License is controversial and has been criticized as being "too vague"; packages are often released under a dual license where the Artistic License is used.