Posted By: Michael Milham - Jan 7, 2013
Tool/Resource: 1000 Functional Connectomes Project
** 1000 Functional Connectomes Project (FCP) / International Neuroimaging Data-sharing Initiative (INDI) Data Release Announcement **

RELEASE NAME: Enhanced NKI-RS ‘Lite’ Release
PROVIDER: Enhanced Nathan Kline Institute - Rockland Sample (NKI-RS)
DATA TYPE: Resting State fMRI (TR = 645, 1400, 2500), Diffusion Tensor Imaging (137 directions/2mm isotropic)

ANNOUNCEMENT: We are pleased to announce the release of imaging data and limited phenotyping (age, sex, handedness) for the first 181 participants of the Enhanced NKI-RS. The Enhanced NKI-RS is a large scale NIMH-funded imaging effort dedicated to the acquisition and open distribution of functional and structural imaging data for 1000 community-ascertained individuals between the ages of 6.0 and 85.0 years old, over a 4-year period. Comprehensive psychiatric, cognitive and behavioral phenotyping are obtained from participants to ensure maximal value in efforts to reveal brain-behavior relationships. Basic laboratory measures are collected as well.

The following scans were attempted for each participant:
- multiband resting state functional MRI (TR = 645/3mm isotropic; 10 min)
- multiband resting state functional MRI (TR = 1400/2mm isotropic; 10 min)
- standard resting state functional MRI (TR = 2500/3mm isotropic; 5 min)
- multiband diffusion tensor imaging (137 directions/2mm isotropic; <7 min).

Additionally, we attempted to obtain the following scans: 1) breath-holding and 2) visual checkerboard stimulation (blocked design).

1) A 24-subject test-retest pilot multiband dataset for this protocol is available:
2) A publication describing the NKI-RS effort (Nooner et al., 2012) can be found at:
3) In order to protect participant privacy, access to the corresponding high dimensional phenotypic data does require a confidentiality and non-disclosure agreement (see Data-Sharing Policy section of website for details; tentative distribution date for high dimensional phenotyping data is Feb 1, 2013).

DATA COLLECTION PERIOD: March, 2012 – November, 2012
SHARING TYPE: Unrestricted, prospective/pre-publication

Michael P. Milham, MD, PhD
Director, Center for the Developing Brain
Senior Research Scientist
Child Mind Institute

Research Psychiatrist
Deputy Director of Human Imaging at the Center for Advanced Brain Imaging
Nathan S. Kline Institute for Psychiatric Research
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