Hello Alfonso,

Will you please clarify when it is advisable to include effects of condition regressors as confounds and when not to?  I am looking at between-groups differences in functional connectivity between an ROI and the rest of the brain during successful response inhibition.  My understanding is that for functional connectivity analyses, I want to include effects of condition as confounds.  However, I would also like to run a PPI analysis using the same ROI as source, and test whether connectivity between that ROI and the rest of the brain is differentially modulated across groups by the condition effects (successful response inhibition, i.e., no-go correct).  In this case, would I want to redo the denoising procedure excluding the condition effect (no-go correct) from the confounds list?

Thank you,
Patrick