Hi everybody!

I have a mixed within-between design that I am dealing with.

I have two groups, each scanned twice, before and after a treatment.
What I want to do is compare the difference in resting state functional connectivity between pre and post treatment between the two groups.
To do so, I have planned to concatenate my two acquisitions for each subject and enter them as two different conditions (let's say pre and post) in first level analysis.
Then, I will use the within-between way of conducting analysis described in the FAQ to look at my effect of interest.

Do you think this is a good way to proceed ?
Is there a cleaner way of doing it ?

Thanks in advance for your answers and tips

Best

F.