Dear All,

I have been using T1 and T2 FLAIR images in W2MHS to determine the effective volume quantification of WMH. However, the results are not satisfactory and many gave NaN or attempted to access xx(1); index out of bounds because numel(xx)=0 as the result. I have tried to adjust the the parameters (cleaning threshold from 0.1-2.5 and probability map cut value 0.1-0.5) but again the final results are still the same. I have looked through the images as well and they should all shows WMH.

Is there anything wrong with the parameters? Or something else was wrong?

I have attached one of the data to illustrate the issue.

Thank you for your help.