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help > RE: second-level analysis in Conn
May 9, 2016 06:05 PM | Alfonso Nieto-Castanon - Boston University
RE: second-level analysis in Conn
Hi Diana,
Yes, exactly, the y-axis in this display informs you of the actual FC values between these two ROIs for each subject, so in this case I would say that these are regions that show no correlations or small anticorrelations in low-severity children while trending towards positive correlations as symptom severity increases.
Hope this helps
Alfonso
Originally posted by Diana Parvinchi:
Yes, exactly, the y-axis in this display informs you of the actual FC values between these two ROIs for each subject, so in this case I would say that these are regions that show no correlations or small anticorrelations in low-severity children while trending towards positive correlations as symptom severity increases.
Hope this helps
Alfonso
Originally posted by Diana Parvinchi:
Hi Alfonso,
I have one question and hope that you can help us with this question. Our analysis has revealed various effects. One in particular is showing a positive correlation between FC and social impairment in children with ASD. I have attached a graph displaying this relationship. On the x-axis, it is plotting symptom severity and on the y-axis, it is showing the FC between two ROIs. This figure is displaying a positive correlation between FC and symptoms severity. Meaning, as FC between these two ROIs increases, social impairment increases as well. However the FC between the two ROIs, in this case, could be an inhibitory or an excitatory one (positive or negative). How can I determine if the correlation between these two ROIs is positive or negative? Could we look at the y-axis and use that information? I would deeply appreciate your help. Many thanks.
Best,
Diana.
Originally posted by Diana P:
I have one question and hope that you can help us with this question. Our analysis has revealed various effects. One in particular is showing a positive correlation between FC and social impairment in children with ASD. I have attached a graph displaying this relationship. On the x-axis, it is plotting symptom severity and on the y-axis, it is showing the FC between two ROIs. This figure is displaying a positive correlation between FC and symptoms severity. Meaning, as FC between these two ROIs increases, social impairment increases as well. However the FC between the two ROIs, in this case, could be an inhibitory or an excitatory one (positive or negative). How can I determine if the correlation between these two ROIs is positive or negative? Could we look at the y-axis and use that information? I would deeply appreciate your help. Many thanks.
Best,
Diana.
Originally posted by Diana P:
Hi,
I have two questions about Conn's second-level analysis and would appreciate your help. We are interested in examining the association between core symptoms of autism spectrum disorder (ASD) (repetitive behaviour, socialization, etc.) and connectivity in three age groups (3-7, 8-12, 13-20 years) of individuals diagnosed with ASD. How do I specify the contrasts in the second-level analysis to examine this question? My second question is what does "beta" in the Analysis results represent in the second level analysis? For example, if I have three groups selected in "between-subjects contrasts" and two Seeds selected in the "Between-sources contrasts", what does "beta" in the Analysis results represent? Many thanks.
I have two questions about Conn's second-level analysis and would appreciate your help. We are interested in examining the association between core symptoms of autism spectrum disorder (ASD) (repetitive behaviour, socialization, etc.) and connectivity in three age groups (3-7, 8-12, 13-20 years) of individuals diagnosed with ASD. How do I specify the contrasts in the second-level analysis to examine this question? My second question is what does "beta" in the Analysis results represent in the second level analysis? For example, if I have three groups selected in "between-subjects contrasts" and two Seeds selected in the "Between-sources contrasts", what does "beta" in the Analysis results represent? Many thanks.