Hi Alfonso
Hi Jeff

I can only join Jeff's thanks for your invaluable guidance in the world of connectivity analysis! It is highly appreciated. After reading your explanation and the reference paper, I am convinced by the value of ANCOVA for this type of analysis. I am unsure whether I understood you right about the practical implementation. Is there no easy way to do it in Conn? If not, would you simply stick to the [1,-1] [1,-1] contrast? Strange enough, at least visually, almost all the found interactions seem to have very unreasonably different baselines in my sample.

Warm regards,
Lucas