Dear Andrew,

Great, I suspected that was the difference based on the areas, but the -1 contrast of Music was very similar to the 1 contrast of the interaction effect (same ROIs, similar t-scores), so I wanted to make sure.

Regarding the BCT, I've already been working with it and made several loop based scripts (for different thresholds) to generate binary matrices and run several of weighted unidirect/binary undirected metrics.

However, with regards to statistical testing, I've only found a way to compare two conditions (i.e. Drug v Placebo or Music v No music), but have been unable to determine how/if to test for an interaction effect using all four conditions. Unlike regular mean scores, I can't subtract the means of the music conditions and then compare those results between drug and placebo. 

Sincerely,

David