help > RE: About direct segmentation, normalization
Oct 27, 2022  08:10 PM | Alfonso Nieto-Castanon - Boston University
RE: About direct segmentation, normalization
Dear Tomoki

The "direct normalization" option in CONN will normalize the functional and structural data separately / independently. The "indirect normalization" option in CONN will do what you describe, coregistering first the anatomical and functional data, then normalizing the structural data, and then applying that same transformation to the funtionals. See Preparing fMRI Data for Statistical Analysis. arXiv. doi:10.48550/arXiv.2210.13564 for more details

Best
Alfonso
Originally posted by tomoki kaneko:
Dear Alfonso, dear developers of the conn toolbox,

I use conn to analyze the functional connectivity. I always use the default pipeline using direct segmentation and normalization.
In SPM12, I coregister structural T1-weighted image to mean functional image using 'coregister estimate', and normalize coregistered T1-wi image to obtain the deformation field. Then I normalize the functional image using the deformation field ( using "normalise write").
When I adapt the direct segmentation to functional and structural images, are the two processing pipelines(functional, and structural processing) interrelated each other? Or is there no interrelation between them?
I want to know the relation between the functional and structural preprocessing.

Thank you in advance!

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TitleAuthorDate
tomoki kaneko Oct 26, 2022
RE: About direct segmentation, normalization
Alfonso Nieto-Castanon Oct 27, 2022
tomoki kaneko Oct 29, 2022