help > RE: Resting State Temporal Delay Analysis or Lag Analysis
Feb 5, 2024  01:02 AM | Alfonso Nieto-Castanon - Boston University
RE: Resting State Temporal Delay Analysis or Lag Analysis

Hi Jennifer,


That's a very interesting analysis but sorry it is not yet available in CONN.


In case it helps, for relatively small lags like those observed in that study it is possible to enter the first-order derivative of the seed BOLD timeseries to analyze lag responses (e.g. in CONN's first-level analysis tab, select one or multiple seeds and switch the option that reads "no temporal expansion" to "add first-order derivatives"). For example, in a SBC analysis including first-oder derivatives of the seed, a negative effect in the "first-oder derivative" term of a seed means that the target BOLD signal is lagging behind the seed, while a positive effect in the "first-order derivative" term means that the BOLD timesreies of the seed is lagging behind that of the target (and the magnitude of the effect is proportional to the magnitude of the lag for relative small lags). 


Hope this helps


Alfonso


Originally posted by Jennifer Siegel :



Hi, 


Before I try to reinvent the wheel, just wondering if CONN has tools to do a Lag Analysis of Resting State MRI data as specified here?  


https://www.pnas.org/doi/10.1073/pnas.1503960112


Thanks, 


Jennifer 


 


 



 

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TitleAuthorDate
Jennifer Siegel Jan 19, 2024
RE: Resting State Temporal Delay Analysis or Lag Analysis
Alfonso Nieto-Castanon Feb 5, 2024