Hi Max,

To look at the differences between pre- and post- intervention you would typically select both conditions in the 'conditions' list and enter a [-1 1] contrast in the 'between-conditions contrast' input (also selecting the 'AllSubjects' term in the 'subject effects' list, and keeping the default [1] contrast in the 'between-subjects contrast' input).

Hope this helps

Alfonso 

Originally posted by max345:

Hi all,

I have a sample of 24 participants, each with pre- and post-intervention resting-state data. Now I want to see if there are differences between pre- and post-intervention in my ROI-to-ROI analyses without having a hypothesis about directionality. I have read that you can use contrast [1 1] for this purpose (which would be a custom contrast in CONN). Is this correct? I also got some results and wanted to investigate them further to see if there was an increase or decrease between pre and post and then got no results at all. Could this be the case and if so, why?

Thank you all!

Best,

Max